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Age 43 & 5 Miscarriages, Is The Next Step Invitro?

10 posts on this thread and the last post was on February 24th, 2009 11:37 AM
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KristiF - January 23rd, 2009 2:16 PM
[Original Post]

I found out about my most recent miscarriage on 12-30-08 and the baby stopped growing at 8 wks 5 days. I saw the heartbeat & the u/s looked normal. This has been hard for me, because this one was the furthest along of all my miscarriages. I opted to do a natural miscarriage, but the baby hasn't passed, so now I may have to do a D&C. I had a conference call (No charge) last night with my husband and Dr. Schoolcraft of the Colorado Center for Reproductive Medicine. They are the #1 Reproductive Clinic in the nation. They said the best option for me at the age of 43 is to do Invitro and have them genetically test the chromosomes of each egg to see if I have any good eggs left. They have a new method to test all 46 chromosomes, so I will know 100% if I have any healthy eggs. It costs about $21K to do this ($16K for invitro & $5K to test the eggs), but they have a 20% success rate for my age group versus less than 5% of most clinics. My local clinic would charge $17K, but their success for my age is less than 5%. If I don't have any good eggs left or if the invitro doesn't work, then the next best solution is an egg donor from a young healthy anonymous woman. The clinic charges $30K for an egg donor including the invitro. Does anyone have any advice for me?


deniseb - January 23rd, 2009 5:39 PM

Hi Kristi, I say if you have the money then go for it. I would research a little more and try find others who may have done the invitro with PGD and or/ the donor egg. I also had 5 mc's. My first was at 32 then I had my son at 33, then 4 recurrent losses between 35-39. Like you, I would get the heartbeat and then it would stop before 10 weeks...very difficult. All of mine had abnormalities (trisomies). I had thought of donor more so than PGD because of the success rate, but then decided to use the money for adoption so at least I would be guaranteed a baby. Now take into consideration that I have a child so it made it easier, if I was childless I probably would have went for donor egg for sure.I fell pregnant again this summer and I am now 33 weeks with a healthy boy (I am 40 in June). I just got lucky, no medication or assistance. I followed a blog about a lady who went for donor and everything turned out great. She had a baby girl and they are so happy. I say go for it...................best of luck!!


Kristin72 - January 23rd, 2009 5:43 PM

Hi Kristi, So sorry to hear of your recent loss..and of your many losses in general. The proposition of the invitro although expensive seems like a good option. Have they done genetic or chromosonal testing after any of your D&C's or miscarriages? IF you are are going to have a D&C then make sure they test the fetus this time. I am 41 have also had 5 losses one Nov6th..a chemical pregnancy at 4w3d. A D&C Oct 8th I was 8w6d. No heartbeat was ever detected. I also had an ectopic last Spet '07. I am pregnant for the 4th time in 1 year. I also have a 2 year old and I lost a baby at 14 weeks had genetic testing and no chromosonal problems found. Anyway, if you have exhausted all the tests and everything seems basically normal and you are getting pregnant..you could chance it again..On the otherhand if you do not have the stamina to go through this again without assistance then go for the IVF.\
As for me I am currently pregnant and was given progesterone to help sustain my pregnancy..I just saw the heart beat yesterday..I am cautiously optimistic things will finally be ok. As you are well aware our eggs are getting older and are not as good..but there is a chance that a good one still exists. I don't know if I am of any help..but I truly sympatize with your situation it is just heartbreaking. All the best to you.


deniseb - January 23rd, 2009 11:17 PM

Kristin72,I have been trying to find you on here from your original post.I posted on another forum the other day asking how you were doing but it must have been a different Kristin.I am so glad you got to see a heartbeat, how far along are you? Keep us posted with your progress.



jademaiden - January 26th, 2009 5:45 PM

Hi Kristi, have you done any genetic testing with your miscarriages, and have you done a miscarriage panel? If you have a D&C, they can do genetic testing on the embryo. If all of your mc's were due to chromosome abnormalities, IVF might be the best option for you... However, if some of them testing normal, I wonder if there is something else going on. Maybe you have a blood clotting factor, or an autoimmune issue. Blood clotting (like MTHFR) tends to show up as a problem as women age. I tested positive with MTHFR and I am on blood thinners. I'm currently 26 weeks pg and I've had 4 previous miscarriages. I pondered the "should I do IVF with PGD?" question several times. What was hard is none of my mc's were tested so I didn't know if it was genetic or not. If I knew I had a chromosome issue, I would have leaned more towards the IVF. I have done IVF before (without PGD) and it's a very emotional and physically intense procedure. With a 20% success rate (or 80% chance of it NOT WORKING), I opted to try other treatments like the blood thinners first.


chandellina - January 30th, 2009 12:21 PM

i'd say go directly to an egg donor because your chances are going to be so much better. But if having a child genetically your own is crucial to you, then go for the egg testing.
good luck!


Delphia - February 20th, 2009 9:43 AM

Kristi - I am very interested to hear about your decision regarding IVF. I may be right behind you. I will be 41 next week and just had my first d&c last week after getting pregnant on first try with new husband (I have no children but two prior pregnancies which I elected to terminate). We want to try again asap. The thing is we want two children which is very ambitious considering my age, IVF may be the only way, I am just beginning to learn about it. I wish you all the best.


comommy - February 23rd, 2009 12:35 AM

I am 36, have ds '01, dd '03, and 3 m/c after 4 yrs ttc, decided to do IVF, just had twin boys 2/6/09 as a result (I saw dr Bush, Conceptions, with higher IVF success rates-in Littleton and Lafayette COlorado. No answers as to why I had recurrent m/c, except for they think I have PCOS, which may or may not have fostered the m/c issues. Al in all, would have loved to do PGD on the IVF cycle, very worried about being over 35 with the embies having trisomies, have 4 frozen and unsure of gender or trisomy status (would love another girl for my daughter, but can't afford the emotional trip or financial trip of doing fresh IVF, don't want another boy to take the chace on our current cycles (our luck they are all boys left LOL!) You have to decide if you want your biological child or a donor egg, no matter,keep in mind, that ultimately, important thing is being a mother that matters, not the genetics of your child. Sometimes God chooses mothers to be mothers of children that are not of their own flesh and blood, but part of their hearts instead, and were thus hand picked by God to do so.



paolan - February 23rd, 2009 10:46 PM

Comommy ,
Before my 20 week ultrasound I tought it would be cool to have a girl after 2 boys just to see how different she would be or maybe not ,well it turned out it was a boy after few min that it settled in I was thrilled to know baby was healty it turned out I lost the baby on the date of my c scetion due to an accident of the cord .Babies are miracle ,boys or girl all that matters is that they are ok and you get to take them home and be a mom . I could not care less if in the future i'm blessed with more boys . Evrytime i look at my 2 boys i think how graet it would have been to have their little brother there with them I 'll miss him forever , You are blessed with 2 lives .


comommy - February 24th, 2009 2:21 AM

Paolin-since reading your post on another place, my hear aches for you and the other lady that posted with you who lost her child at 39 wks w/placental abruption (sorry I forgot her name). Don't get me wrong at all, I know these little boys are a true miracle, esp since my pregnancy was riddled with complications from the get go, on bed rest a total of all but 6 wks of the whole pregnancy for everything from sub chorionsic heatoma, treatened miscarriage, plaental abruption of one twin, and preeclampsia and after many long months of bedrest for this, took a severe turn for the worst in a matter of hours to where I had to have an emergency c-section. They didn[t find the heartbeat of baby B for a while just before the csection, and when he came out, the cord was around his neck so tight that they could barely cut if off. Thankfully it all turned out ok after arriving 1 month early, and they are both home, on oxygen after 1 week in the nicu. It's strange that through this pregancy I yearned for my previous losses,, although if I didn't have the losses, we wouldn't have been having these miracle twins, we wouldn've been done back then . I can't imagine what you must be groing through, it truly is horrible and you are in my prayers. I will always yearn for another daughter for my Annika, but we are all in love with these boys as well.


paolan - February 24th, 2009 11:37 AM

Commommy
Thanks.
I know te feeling ,Having lost this baby boy makes me want another boy in my next preg but I think my mind is playing the trick that what I really wish for is bringing my lost angel back to life and I know that 's impossible I have to live evryday knowing and accepting that.
Thanks again. Best to you and your miracles.