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I'm sorry Jessica - that sucks. Getting a BFN last month was really hard on me. This months cycle is strange. I'm CD 10 and usually get a high around now but so far I still have a LOW with my CBEFM. I have a feeling that all this B6 that is in the Folgard vitamin might be screwing with my cycle a little bit. So I'm just waiting to ovulate. Would love to get a BFP this month and surprise DH on his birthday. I'm feeling okay I guess just anxious ya know? Thanks for asking. Have a good weekend - it's almost here!

Here's my background: In march My daughter was diagnosed at 19 weeks with anencephaly. I was induced at 20 weeks. I requested the MTHFR test after speaking to a genetic counselor. I'm a compound heterozygos (G677T and A1298C). I'm supposed to wait at least three more months, i'm going to talk to the dr. on tues. this forum has been so informative and I'm hopeful that i'll have a healthy baby in the future!

Belle, sorry for you loss hun. Definately start taking that folic acid now along with B6 and B12. I just buy mine at Walgreens but there are some scipts out there that you can get too. Cloud9, any change on your CBFM? I know B6 can lengthen your LP so maybe its lengthening your entire cycle?? As for me I am 14dpo, still BFN and still getting signs AF is coming. I predict she will be here on Sunday right on schedule. =(

Jessica, Sorry that AF is on her way to you. I hope you get a BFP next month! BELLE, I'm so very sorry for your loss. Anencephaly is tragic but you'll have a healthy baby in the future. I'm also compound heterozygos (G677T and A1298C). Ask your doctor for a prescription of Folgard. It's a combo pill with 2.2mg of folic acid, 25mg of B6 and also has B12 (not sure of the amount). I also take another 2mg of folic acid a day in addition to the folgard. Our poor little babies just couldn't develop properly without this vital nutrients. Mine stopped growing at 7 weeks. Again, so very sorry for your loss. Hang in there!

jessica, keep me updated. I'm ovulating now and I'm chock full o' vitamins so keeping my fingers crossed. This month I'm using pre-seed and trying the instead cups to help keep all the spermies up there! I'll also be eating the pineapple core to help with implantation starting on 1dpo. Keep in touch!

LOL, I've heard that about the pineapple core! Let me know if it works, I may just try it. Its CD1 again for me =( so starting all over again. Hope you're getting lots of BDing in! Let me know when you decide to test.

I just got back from the dr. he is running more tests to check my homocysteine levels, but prescribed metanx. I know a lot of you are taking extra folic acid. part of MTHFR is the inability to covertt olic acid into methylfolate which is what the body uses. Metanx is methyfolate, there is no converting, so our bodies can absorb it. it also has B vitamins. here is more info for anyone interested... google metanx and click on the tab that says unaffected by the MTHFR polymorphism at the top.

thanks belle! good info! sounds like your appt went well :)

I hadn't heard of metanx I will have to look that up. Thanks Belle!

Hi ladies - I hope you don't mind me asking some questions. First let me give you some background. DH is 34, I'm 33 - we've been ttc for 2 yrs. I had a missed m/c in Nov 06 and a chem in Feb 07. My OB chalked it up to a "fluke" and refused to do any testing since I had only 2 losses - but she said technically one since she wasn't counting the chem. So I switched to an OB who started b/w right away. I went in for several different b/w appts and everytime was told "normal and fine." DH had an SA done and we were told everything was "normal" in that dept. SO....we kept trying and now that we are passing our 2 year mark of trying - I switched to an RE. I've only had one appt w/ him and will be going through the HSG next week to check my tubes. In preparation to switch to my RE I filled out the forms to have my medical paperwork sent to him so he would have my history. The OB office sent them to my home where I started to read and go over them. It showed that my Beta-2 Glycoprotein IgM was HIGH....and my Antiphospholipid IgM was also HIGH. I started to do some research of my own b/c I was confused on why I was told everything was fine and normal when it didn't appear that way in black and white. ------------------- so my question is: Does anyone have any knowledge of High Glycoprotein? I found some stuff on the internet which reads -------------------- Antiphospholipid autoantibodies particularly antibodies against beta2-glycoprotein I (anti-beta2GPI) are casually associated with thromboses in patients with autoimmune diseases. In conclusion, we found that levels of IgM anti-beta2GPI are increased in young women suffering arterial or venous thromboses in the absence of other known autoimmune diseases and also in the absence of pronounced classical risk factors. We found that IgM anti-beta2GPI positively correlated with some markers of increased coagulation potential and negatively with parameters of the metabolic syndrome. Thus, it appears that elevated levels of IgM anti-beta2GPI are linked to thrombotic disorders in young women (without autoimmune disease) particularly when classical risk factors or the metabolic syndrome are absent. " ------------- there is a history of stroke in my family and I'm very concerned and nervous - could this be the reason for my recurrent losses or why I can't seem to get a pregnancy to stick? I feel foolish b/c I should have pressed the OB but I trusted her and now feel like a complete failure - I've lost so much time and just don't know where to turn. If anyone can help me understand, I would be forever grateful.

Hey pba, so sorry for your losses. I can say that you are so right in following your instinct to a new doctor! good for you! If I were you I would get to a rheumatologist immediately to make sure you don't have an autoimmune disease - not saying you have one at all just get checked out by a specialist. Sounds like a clotting disorder. I also had a m/c and a chemical pregnancy and I'm 100% that I will be able to have healthy children even though I have ANA and MTHFR. Try not to worry too much but continue being proactive about your health care. Good luck and keep us posted.

thanks Cloud0 - not to sound completely clueless even though I am, what is a rheumatologist? I was actually thinking of going to my primary care doctor for some answers. I feel really comfortable with him.

pba, a rhuematologist is a specialist of autoimmune disorders. He/she would be your best bet at telling you if those antibodies are an indication of an autoimmune disease or if the antibodies alone without a disease is your only risk factor and where to go from there. If you are comfortable with your primary doc, that would be a good place to start but honestly they seem completely clueless when it comes to this kind of thing, but at least he could give you the referrals you need. It seem to me that the effect of thrombopilia and autoimmune disorders on pregnancy is fairly new out there and sometimes you have to find the right doctor in order to find the right answers. But there are doctors out there who specialize in that kind of thing and maybe your primary care doctor knows one. Good luck hon, keep us updated if you can.

Thanks Jessica - my husband is setting up an appt with his doctor who is a cardiologist. I know it makes no sense but he is the best in the business. A real genius is what all the nurses, doctors and my husband call him. So we will meet w/ him and he will be referring me to a doctor he feels will fit my needs. I feel so lost and grabbing for this answer or that answer. It is scary not knowing who will be guiding me in the right direction - some doctors care a lot and some don't. My husband is 150% confident in his doctor to help us and for that I'm grateful. Thank you all for your input and suggestions. It has helped out and for now it is one step at a time to get me on the road to having a baby. Thank you all again.

Hey Jessica! Well, good news! I'm pregnant! I tested this morning at 11dpo and just went to have my betas drawn. I'll let you know when he starts me on the prednisone and the lovenox. I'm scared but hopeful! 3rd times the charm? I feel like the folgard will give me a fighting chance this time. I'll let you know what my betas do and again, tell you what the doc puts me on and the amounts. How are you??

OMG yay Cloud9, LOL. We must be on the same wavelength cause I got here right when you posted. Woohoo, I'm so excited for you. Here's lots of sticky baby dust! *+..+**+..+*+..+*+.+**+.+**+..+**+.+*+...