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Susanna - December 17th, 2004 3:08 PM

I just had this test done and was wondering what the blood test will tell you exactly.


Christine - December 17th, 2004 4:01 PM

The blood test/amnio...are supposed to be able to tell you if your child is carrying such abnormalities as down syndrome, spinal bifada...or a few others...the blood tests have a high false positive outcome...which means if it comes back positive it is not 100% and they will do an amnio...they also have a high false negative...which means that even if they come back normal...you could still be carrying a baby with these abnormalities...but they probably wont do further testing because you had a negative answer...to me they make no sense...Doc told me that too..not that they didnt make sense but about how they can be wrong a lot...might as well go straight for the amnio if your going to test(even though they dont usually offer that until given a possible positive result)...that is what they are supposed to tell you though...amnio's are much more accurate...good luck...I forget what the name of the test is right now, but you can look it up on the internet...I did it back when my doc offered it to me


Christine - December 17th, 2004 4:47 PM

Was doing some reading on internet...found this for you

"The second trimester of pregnancy may involve test-taking anxiety for some women. If you are over age 35, or had disturbing results from other tests, your practitioner will recommend amniocentesis, which checks for conditions such as Down syndrome. While one in 200 women experience problems as a result of the amniocentesis which could, potentially, lead to miscarriage, the odds of having a down syndrome child are higher. By making sure the technician performing this procedure has solid experience with good results, you can further lower your chances of complications.

A common blood test called the Maternal-Serum Alpha-Fetoprotein (MSAFP) screening, which is offerred to women between weeks 16 to 18, is also used to identify potential problems with the fetus. In some cases, results can be misleading and cause needless worry: 50 in 1,000 women will have poor results and only one or two of the original fifty will go on to experience actual problems. One common reason for unusual results is that the pregnant women is, in fact, carrying multiple fetus’. However, for many women, test results will bring great relief.

At about twenty weeks, your uterus will extend beyond the belly button. An ultrasound can clearly identify gender. If you are carrying a girl, she already has six million eggs in her ovaries. By birth, the amount of eggs will have decreased to one-sixth this amount."

Hope this helps some...


Reb - December 20th, 2004 6:09 PM

I had a first trimester screening done that gave me a really good adjusted risk for downs. It changed my age related chances of having a downs baby from 1/140 to 1/898. Then I had the blood test in the second trimester, and got a 1/78 number. I ended up having to have the amnio to put my mind at ease. It all turned out fine for us, but don't believe the AFP number. There are over 25% false positives or false negatives. The doctor who did my amnio thought the AFP number I had received had been bogus because he knew about the 1/898 number, which he considered more accurate. I was scared to death of the amnio, but more worried about being stressed for the next 5 months that the baby had downs. There is a chance of complications because of the amnio, and that is going to someone who does these everyday, which I would recommend if you go that route.


AMBER - February 2nd, 2005 4:06 PM

I HAD MINE DONE AND IT CAME BACK POSITIVE AND I MADE THEM RE TEST AND IT CAME BACK NORMAL SO THE TEST ARE MOST LIKELY NOT ACCURATE


Amanda N - February 8th, 2005 2:13 PM

I opted to not have the test at all. Due to my doc saying they aren't too accurate and from two people I know being told their babies had Down Syndrome and then when they were born they were both fine. So I decided it wasn't worth the stress.


muthaluv35 - July 22nd, 2005 5:14 AM

I'm 4.5 months pregnant and I have not gained 1 lb. And I recently got a postive blood test that my baby has downs. Also I am 41yrs old with 3 prior miscarriages. Is everything going to be okay?


Amanda - July 22nd, 2005 10:21 AM

Did you have a triple blood screen or a quad blood screen??? The triple blood screen has a very high false positive rate where as the quad has only a 5% false positve. I had the quad test done and everything came back normal. I would try not to worry too much until you have a level 2 ultrasound...i would opt for that if i were you since an amnio could lead to miscarriage. If everything checks out good during the ultrasound then everything should be fine :)


Steph - July 22nd, 2005 10:58 AM

I had this blood test done with a positive outcome for downs syndrome - very scary at first, but like Christine sad, there is a high area of gray where there are a lot of false positives. If you test positive, they will want to most likley schedule you for a Level 2 Ultrasound once you are 20 weeks or more which is basically the same as a regular ultrasound, but a higher certified doctor comes in who is able to look closer at the chambers of the heart and do some measurements of the baby associated with Downs Syndrome. After that they will tell you how they think your baby looks and leave it up to you most likely whether or not you want to have an amnio done or not. My husband and I got it done mainly for our peace of mind and everything came back perfect and we are 100% having a little girl. Downs Syndrome is a chromosonal abnormality and is characterized by there being an extra 21st chromozone in the baby's DNA. Through the amnio they are able to collect all of your babies chromozones from the amniotic fluid around the baby and map them out to make sure they all match up and there are no extra or less than there need to be for a "normal" baby.

Hope this helps. I wish you all the best and just remember that if you do get a positive blood test, that is not the end or the definate answer. The amnio is the only way to know 100% if everything is okay, but the doctors do know what they are doing and usually can resassure you that things are fine or that you should have the test done. Good luck and God Bless!


Tati - July 25th, 2005 11:01 AM

Our friend has 5 children she was pregnate with the sixth when she was around 37years old. The doc did the test for down syndrome and they told her that they had to do the other test. They put a long niddle in the stomach and took some of the fluid that they baby is in. That came out bad too. So they told her that with the age and the tests they recommend a abortion. But she said NO. It was wrong to even think like that. She had the baby. That little baby was born not only with perfect health but with a beauty that everyone notice. Now the little girl is almost four and very health.


Tatyana - July 25th, 2005 11:04 AM

Our friend has 5 children she was pregnate with the sixth when she was around 37years old. The doc did the test for down syndrome and they told her that they had to do the other test. They put a long niddle in the stomach and took some of the fluid that they baby is in. That came out bad too. So they told her that with the age and the tests they recommend a abortion. But she said NO. It was wrong to even think like that. She had the baby. That little baby was born not only with perfect health but with a beauty that everyone notice. Now the little girl is almost four and very health.


sarina3 - March 16th, 2006 10:26 PM

Just wanted to let people know that I had this test done and it gave my husband and I a real scare - we were 1 in 341 chances for Down Syndrome which was 'higher than usual' for my age group - we did a detailed ultrasound and everything looked perfect -the technician told us that she would never get this test done if she got pregnant!! Many women that I have spoken to since get a scare as well when their test shows a higher probably for risk than they should have... We were very nervous and it threw us into a mix of difficult emotions for weeks - we decided against the amnio (1 in 200 chance of miscarriage) because of the math... We gave birth to a beautiful, healthy baby girl on Feb 21. So, if you get the test done (which I would actually not advise!!), please try not to worry too much even if it shows that you are 'above the average' risk for your age, etc.. The odds are good that your baby will be perfectly fine.


JenniferB - March 20th, 2006 2:30 PM

I have known a few people that have had the tests and were given a scare with no cause. I wouldn't bother having it done simply because it wouldn't make any difference. I would have the baby regardless of the results. The only reason to do it would be to prepare yourself but it would be awful to have your entire pregnancy more stressful than it all ready is with a false positive.


Carieg - April 5th, 2006 6:56 AM

I am 32 y/o w/my first pregnancy & just got my test results back from my quad test that indicated my baby has a 1/184 chance for DS. Even though my chances seem slim that I may have a DS baby I am still going to have the amnio. I have appreciated reading this blog b/c it has eased my mind some especially reading about all the pregnancies that ended up perfect after a scare of DS.


elisabeth - April 5th, 2006 10:09 AM

i'm 23 and i had the blood work done to see if anything was wrong. now i have to go in tomorrow and have a level 2 u/s done with a possible amnio but i'm not doing the amnio. if they can't fix the problem (if there is one) and i'm not going to abort then why should i have the amnio done?? my chances are 1/174. i hope they aren't accurate this is my 1st baby and i can't imagine anything being wrong. i'm so scared.


HannahBaby - April 5th, 2006 12:55 PM

i didnt get the test because i knew that an amnio was the next step and i knew that i would never get an amnio. Those tests seem to be VERY unreliable, and to get an amnio and risk miscarriage over not very accurate test results is crazy (unless you have downs in your family then i would definatly get the test) Good luck to all you women who have gotten positives.


EM - April 5th, 2006 1:52 PM

My friends sister had this test also and they told her she had a 1 in 200 something chance of downs. Her father in law wanted them to abort immediately and it caused a huge family fued. In January she have birth to a perfectly healthy baby girl...I would never get the test done simply because even if the test could tell you 100% your child WILL have ds, I wouldn't do anything about it.


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