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Avollmer, I also can't thank you enough for your response! I too have had 3 miscarriages and have prometrium sitting waiting to take. Ive just had my first period after the last miscarriage and was wondering about taking the prometrium before finding out I was pregnant. I am wondering about the accuracy of detecting ovulation? Chantal and Jonelle, are you really sure that you are waiting long enough after what you think is ovulation before taking the prometrium, cause if you have luteal phase defect then ovulation is later and you may actually be taking it during which may be hindering the ability to conceive - just a thought, although I'm sure you know by now your cycle. Certainly makes me think you should try it once without the prometrium - anything's worth a try eh? I think I'll wait for a positive test now after hearing what all you guys have to say about it. I can usually detect about 4 days before a test is due if I am pregnant due to sore boobs etc so that's another option for you chantal if you want to try it that way. Hopefully success for everyone this month then!

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