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~m~: My doctor just put me on 200mg Prometrium once per day, as well -- for more or less the same reasons: I miscarried this past June at 9 weeks (7 weeks since conception). As soon as he found out I was pregnant this time (at 3 weeks since conception), he tested my progesterone level. It was 10, which is apparently the very bottom level of what's still acceptable; most doctors like the number to be 14-20. So he put me on Prometrium and I am electing to use the pill as a suppository. I know it sounds totally bizarre to shove a pill you'd normally be swallowing up your vaginal canal like a tampon -- but I swear by this method after reading so many other women on this forum (thank God for this forum!) and on other online sites say that the suppository/vaginal method is more effective than the oral method. If you take it orally, your liver processes it and the half-life is 4 minutes. Whereas, if you use it as a suppository, you're literally getting it directly to the cervix and then the placenta. This may sound insane, but my doctor told me I could take it orally OR vaginally -- ask yours to confirm, but the spotting I had been having this time around immediately disappeared after ONE vaginal dose of Prometrium! Good luck with your pregnancy and try not to worry; I know it's hard not to, after even just one miscarriage.

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