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Hey ~m~! From what I understand, Progesterone is a hormone that your body makes to support a pregnancy. When a woman doesn't make enough of this hormone herself, the pregnancy always ends in miscarriage. Prometrium is Progesterone, just in the synthetic form. My friend had to take it for her first trimester only and then her body took over from there. She's due in June and is having a very easy pregnancy. Hope this helps.

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