Hi melaniepeachy: I've continued to research/read about Prometrium during the first trimeseter, and have met/talked with many women who have used it in every pregnancy and have perfectly normal children. There are slight risks, but NO clinical studies have ever been done on pregnant women using Prometrium during pregnancy. I read there is a risk of cleft palate or club foot in the baby; I'd rather have a baby with those slight abnormalities than not have a baby at all. I just had my 19 week ultrasound and our baby boy so far looks perfectly normal; I stopped taking Prometrium (200mg once/day, taken as suppository) at my 13th week. If you feel uncomfortable with Prometrium, consider using a natural progetserone cream instead. One place that sells it online is a natural, organic pharmacy based in Aurora, Illinois called The Compounder. Just google The Compounder. That website also has an excellent pro-progesterone during pregnancy article worth reading. Good luck! I stopped spotting after ONE dose of Prometrium; it works!
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