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Twins, fraternal at least, tend to run on the maternal side because a hyperovulation gene is inherited which causes the female to ovulate more than 1 egg at once. If twins are seen on the paternal side, the gene could have been inherited by the father, but of course is silenced because he does not ovulate. This is also why twins can be thought to skip a generation, because if the woman inherits the gene from her father, he obviously was not affected by it. So, a man with a family history of twins is not more likely to father twins himself, however his daughter could be likely.

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