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Kendra.marie. If you tell your OB that you want the downsyndrome test then you have an ultrasound at anywhere between 12-14 weeks gestation. It's a blood test and then and ultrasound. I was also told that by my OB, but I wanted to make sure both sacs were still there so I opted for the test. I didn't really have any other signs that it was twins, my pregnancy blood test didn't come back any higher than normal which surprised me.

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