Lia -- I'm also on zofran here, prescribed 4mg up to every 8 hours. Started at that dose and now take only one pill daily. I'm at 12w5d and finally have the nausea/vomiting under control. It was a lifesaver - I was sick for 9 straight months with my son and actually lost 15lbs overall by the time he was born. This was not something I was willing to go through again, so zofran is my friend. Headaches are a common side-effect but are also common in pregnancy.
My good friend whose husband is a pharmacist used it for all her pregnancies, had 3 kids perfectly healthy. Another friend also used it for three pregnancies, one of her daughters born with a hole in heart that resolved itself by 4 months - of course this is not that uncommon and can't specifically be attributed to zofran - the other two kids perfectly healthy.
That said, if you can't eat or drink, the baby may already be in danger so you need to balance that risk with the risk of a drug that is routinely used off-label in pregnancy.
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