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I think with any drug you need to weigh the risks vs. the benefits. Having worked in a teratology/embryology research lab for the past 5 years I am able to sift through the publications on this drug and as it stands now there has been no good clinical trials to say that whether this drug is or is not safe for the development of the fetus. The only real human study done thus far "Placental transfer of ondansetron during early human pregnancy, Siu SS." showed that the drug was found in maternal venous blood, coelomic fluid, amniotic fluid and fetal tissue. Since this drug is a 5HT3 receptor antagonist and that's key to proliferation, differentiation and migration of the central nervous sytem neurons as well as chondrogenesis it is possible that the drug could have an impact and it could be so long before you ever knew that it'd be difficult to correlate the defects back to the drugs. As a result, I think I'm just going to choose to suffer for a bit longer and just hope that it goes away.

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