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Hey Jessica! Thanks for starting this new thread. It took me about 5 hours to read through the old one but I gotta tell you, I learned so much from it. I feel hopeful again that I'll be able to carry a baby to full term. Here is my story... I had my first miscarriage back in November of 2007. A blighted ovum was discovered at 7 weeks. I had a d&c and was told to try again after waiting two cycles. I was lucky to get pregnant again the first month back trying. That pregnancy resulted in a chemical pregnancy at 5 weeks. My doctor requested blood work and I got the results last week. I am compound heterozygous for the C677T and A1298C gene mutation MTHFR. I also tested positive for ANA (antinuclear antibodies) my titer level is 1:80 so just barely over what is considered "normal". My OB says that she believes that these mutations caused my m/c's. She has instructed me to take a baby aspirin every day the second I get a positive pregnancy test. For the MTHFR I'm taking 5mg of folic acid, 1000mcg of B12, 200 mg of B6, 1 Stuart brand pre-natal vitamin and 2400mg of Omega-3 fish oil. I'm seeing a rheumatologist at the end of the month to rule out any autoimmune disorders. I've already tested negative for lupus. I was so very thankful for that. Needless to say, my m/c's were heartbreaking and devastating to my Husband and I. I do feel a sense of optimism now that I know what is wrong with me because I feel that with the vitamin and aspirin regimen, we have a really good chance of having the family we want so badly. I'll be 37 years old in a month so I feel like the clock is running out a little bit. I would love to hear a story of a successful birth with someone that has both the MTHFR mutation and the ANA. What's your story Jessicab3?

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