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Stefkay - there is a lot of information out there that gets misunderstood I think. I will tell you what I learned from my OB who did a huge trial on miscarriage and progesterone many years ago and is still learning every day. There was a risk of deformities if you take an oral pill because during the digestive process it actually changes form and absorbs into your body differently than a natural progesterone and that is why suppositories were so widely used. Now we have progesterone in pill form, such as Prometrium, that is coated in peanut oil and the digestive systems/acids etc cannot destroy it and it stays in its true form to be absorbed. However, congenital abnormalities/deformities or an early miscarriage can be caused by the use of chemically altered progestins. These progestins are not progesterone and a doctor knows that. These chemically altered or synthetic progestins will destroy a baby, but progesterone is essential for the development of a baby. As for progesterone sustaining a pregnancy that has chromosomal defects that is not the case. Most pregnancy losses are due to genetic abnormalities present from the point of conception. Progesterone may prolong such a pregnancy, but it will not prevent the destined loss. There is no evidence that progesterone supplementation has a detrimental effect on the embryo or fetus other than a postponement of the inevitable miscarriage. I hope that makes sense. Women with low progesterone aren't doing some kind of harm to their body by taking the progesterone....in fact we do more harm not taking the progesterone even on a daily basis when not pregnant....it is naturally suppose to be in our system.....you hear all this talk about estrogen dominance....well, what do you think we have if we have no progesterone...we are estrogen dominant and this dominance in the estrogen we have is very clearly linked to breast cancer, uterine/ovarian cancer.....okay....I am babbling...sorry....I could go on and on - LOL!

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