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I read this and it really helped me prepare for my own misoprostol-induced miscarriage, so I swore that I would write up my experience as well. I discovered a blighted ovum at about 8 weeks (counting from LMP). This was Jan. 3rd. The empty sac grew to about 2.5 centimeters with no evidence of an embryo inside. My dr. told me to wait 2-4 weeks for it to naturally miscarry but I really didn't want to wait that long. Plus I read online that blighted ova are much less likely to naturally miscarry. I had no signs of miscarriage at all. No spotting or cramping at this point (though I had spotting at around 6 weeks that just stopped after a few days). So 1.5 weeks later I decided to try misoprostol (Jan. 14th). They told me to take it at night and just go to sleep but I had heard it could be quite painful so I took it (800 mg - 4 pills by vagina) in the morning, around 11 am. I wanted this to take place while my Dr. was still in the office. I felt nothing for 3.5 hours and then I felt cramping pain (no bleeding). I had been given a narcotic, vicodan, for the pain but I didn't take it right away because i wanted to be able to monitor the true pain. I took ibuprofen only. Then in a matter of minutes I felt much much worse so I took the Vicodan. But I think it took some time to kick in because I just felt worse and worse and finally I was beside myself with pain. I couldn't keep still. I would use the toilet with diarrhea and rock back and forth in pain. Then just lie down on the floor in the bathroom and rock back and forth. It was so horrible that at one point I thought I just couldn't do it. It's the worst pain I've ever felt. My boyfriend was there but i couldn't handle him touching me. He just sat there and watched me while I writhed in pain. I had a little tiny bit of spotting but that's all. Possibly because I was mostly lying there on the floor and not sitting up. After about 45 min to 1 hour the vicodan kicked in fully and i was able to move to the couch and lay there, still very much in pain but calm enough to stop rocking. I fell asleep after a few minutes and woke up with more pain about 2 hours later. I took a second Vicodan and again felt better. If I had to do this again I would take the Vicodan RIGHT AWAY at the first sign of cramping. The pain I felt was excruciating until the Vicodan kicked in and then I was able to be still and take it. I took more Vicodan 3 hours after that (the pain was really starting to come back) and then the cramping subsided. However, the odd thing was that through all this I had a bit of bleeding but not a lot and no clots had come out. Around 11 pm at night I had a couple of big slabs come out. I say slabs because they were quite firm and unlike normal period clots. 1 X 3 inches or so and about 1/2 in or so thick but quite firm. I think I also saw a small grey shriveled sack. Very easy to miss -- all shriveled up it was about 1/2 the size of a small pea. That was it. Bleeding only after that, I went to the dr. 3 days later and they said it looked like a complete miscarriage, but i still had some lining left that she thought i would shed normally. She also did a pelvic exam and found some additional odd pieces of riggly material stuck in my cervix. She pulled it out. Then she tested my hcg which was about 1800. I continued to bleed a bit (not much). 11 days later my hcg levels were 17 so the Dr. thinks this is evidence that I really had a complete miscarriage. I had really doubted it that first day (night) because I had had so little bleeding during the day and just a couple of large clots came out 12 hours after taking the medicine (which seemed late to me). I was very demoralized and then the first read of the ultrasound was that it was incomplete because of the lining still present. But the dr. thought it was not POC and just normal lining and would come out naturally. I continued bleeding/spotting for about 2 weeks total, from the day of the medication.

Anyway, I thought my experience was a bit unusual and might help people not worry if they experience something similar. Also, be sure to ask for a narcotic if they don't offer it. I don't know what I would have done without it. I would have gone to the ER for medication, but moving would have been horrible.
Good luck to everyone. This forum helped me prepare for mine.

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