Clomid And Recurrent Pregnancy Loss

5 Replies
Alley - November 4

I'm 27. My husband and I have been together for 11 years and have no children. We started ttc this February. In the last 9 months, I have miscarried 3 times, each at 5 weeks. I've done most of the testing except genetic testing. I am trying clomid for my first time. I took it days 5-9 this month, had LH surge yesterday and started taking progesterone by mouth last night. (I took progesterone with my 2nd pregnancy but still miscarried). Are there any success stories out there of someone taking clomid to prevent miscarriage?

 

stefkay - November 4

I've never heard of taking clomid to help prevent miscarriage, but your m/c history sounds a lot like mine (3 in the past year and I am currently almost 5 weeks and hoping this one doesn't m/c as well but I am spotting). I wondered about this because I thought maybe if the eggs are the issue, clomid would help bring forth the good eggs or help them mature more. What did your doctor say? I'm very interested!

 

Alley - November 4

Stefkay, My doctor didn't explain a whole lot to me about clomid but I've done a lot of research online. I've read that one possible cause of m/c is having a luteal phase defect...your body may not produce enough FSH during the follicular stage resulting in inadequate follicle development. Poor follicle development can also lead to less secretion of progesterone which is needed to maintain a pregnancy. Anyway, clomid helps the body to produce more FSH so I think that is why it would help someone like me. I'm not sure if the doctor had the same thing in mind, it's just my best guess. Do you have any children? I hope this pregnancy is successful for you. I had an LH surge yesterday and am still surging today. I should be able to take a pregnancy test in about 2 weeks. I'm so scared to be pregnant again and have the constant worry of m/c...

 

stefkay - November 4

Wow, sounds so much like me...I have spent most of the past year researching and know a lot about the luteal phase defect. I remember now reading what you described. I recently dumped my OB, RE and perinatologist after tons of testing and moved on to a different RE at a universtiy hospital who has worked extensively in recurrent loss. I got my bfp 2 days before seeing him so he just put me on progesterone regardless. He said testing for an actual luteal phase defect is hard to do even with a biopsy so he explained that research has shown progesterone to beneficial after all so he prescribes to his patients most of the time whether progesterone tests come back normal or not (levels fluctuate so much during the day you would have to test every 2 hours daily to get a good picture of prog. levels and that just isn't possible. Clomid will help up prog. in the second half. Not sure if it gives the same effect if you just start progesterone 3dpo or not, but that is what he said he would have suggested had I still been ttc. I'm leary of clomid right now but would be willing to try if he suggested it. I'm going to hope this one makes it first, then if not we have some more things to look at before I try again. I don't have any children yet which makes this all the harder. So you have had most of the testing? We had the genetic testing done too, but it came back normal and most do so I don't know if it worth all of the money...

 

stefkay - November 4

Oh, and good luck to you in 2 weeks!!! Just don't give up...it is scary, but at this point I'm more p__sed off than scared, lol! ;)

 

Alley - November 4

Stefkay, Thanks for the great info. I have only been seeing my regular OB/GYN. If I have another m/c, I think I will look for a specialist. It sounds like your new specialist gives you a lot of explanation which is great. I know what you mean about being p__sed off. What's really difficult for me is that it seems like all of my friends are suddenly pregnant and having babies. I can't even bring myself to go to their showers. They don't understand and I just don't have the energy to try and make them understand. I've read a lot of comments people post on this site but today I became a member (my first time) and I think this will help me a lot. I didn't realize it was so difficult to test for LPD. I've had a lot of bloodwork and a hysteroscopy and everything came back normal. I'm really hoping the clomid treatment works, I haven't had any horrible side effects like other women I've read about...apparently the clomid is supposed to increase estrogen which in turn increases progesterone, which is how my doctor explained it. She didn't think the additional progesterone was necessary but agreed when I requested the prescription...goodluck with everything.

 

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